Restylane heritage & safety

Safety and reliability

Restylane's record of efficacy and safety has resulted in a range of products that you and your healthcare practitioner can trust.

  • World’s first stabilized and FDA-approved non-animal HA filler
  • Over 23 years of clinical legacy
  • Over 40 million treatments worldwide
  • Over 6000 patients followed in clinical trials
  • Over 150 scientific publications and 40 randomized controlled trials
Over 40 million Restylane treatments
Over 40 million Restylane treatments
Publications
Over 220 scientific publications and randomized controlled clinical trials in aesthetics
23 years of clinical legacy
23 years of clinical legacy

Today, Restylane has the broadest range of HA-based products backed up with decades of clinical experience demonstrating safety and long-lasting results. Whether you are looking to smooth away wrinkles, add definition to facial features or simply improve the condition of your skin, there is a Restylane product tailored to your needs.

Speak to a healthcare practitioner to find out more.

Healthcare professionals and patients across the globe use Restylane

Learn more on the reasons why healthcare practitioners are confident using Restylane.

How Restylane came to be

In the late 1980s, Swedish scientist and entrepreneur Bengt Ågerup had a vision to bring his scientific work on hyaluronic acid out of the lab and into the real world. Ågerup and his fellow scientists wanted to find a way to restore skin moisture and structure by creating a product that could deliver naturally occurring hyaluronic acid into the skin.

The product was Restylane, the world’s first stabilized non-animal hyaluronic acid filler, formulated with patented NASHA™technology.

And the innovation didn’t stop there. Since Restylane was launched in 1996, the development of proprietary Optimal Balance Technology™ offers new ranges of products that have been developed to suit patients’ individual needs. Diverse textures offer different levels of lift or volume, and some products are focused on improving the smoothness and appearance of the skin. Your healthcare professional now has a range of innovative Restylane solutions to tailor treatment to you – whether it’s to smooth wrinkles or lines, enhance facial balance, volumize your lips, or get a more radiant-looking glow. Or, all of these combined!
 

23 years of proof in real life

Louise, 65 years old, from Sweden, was one of the very first patients to be treated with Restylane in 1996. Louise has been continuously treated with Restylane over the past 23 years. She will continue to use the product to help her keep her natural look as she ages gracefully.

“Restylane has made me look like I feel. I like to feel fresh and like the age I am, not older. I feel amazing. That’s important to me.”

 

Louise

See what patients think of Restylane treatments