Restylane heritage & safety

Safety and reliability

With its rich legacy and established safety profile, Restylane is a name you can trust.

  • World’s first stabilized non-animal hyaluronic acid filler
  • Over 25 years of clinical legacy
  • Over 50 million treatments worldwide
  • Over 6,000 patients followed in clinical trials
  • Over 150 scientific publications and 40 randomized controlled trials
50 Million Treatments
Over 150 scientific publications and 40 randomized controlled trials
25 Years Restylane

Today, Restylane offers the broadest range of hyaluronic acid gels available, with over 25 years of clinical experience. Whether you are looking to smooth away wrinkles, enhance facial balance or simply improve the elasticity of your skin, your healthcare professional can tailor your Restylane treatment to your needs.

Speak to a healthcare professional to find out more.


Healthcare professionals and patients across the globe trust Restylane

With 25 years of clinical excellence and over 50 million treatments worldwide, see why Canadian healthcare professionals are celebrating 25 years of Restylane.

How Restylane came to be

In the late 1980s, Swedish scientist and entrepreneur Bengt Ågerup had a vision to bring his scientific work on hyaluronic acid out of the lab and into the real world. Ågerup and his fellow scientists wanted to find a way to restore skin moisture and structure by creating a product that could deliver naturally occurring hyaluronic acid into the skin.

The product was Restylane, the world’s first stabilized non-animal hyaluronic acid filler, formulated with patented NASHA™ technology.

And the innovation didn’t stop there. Since Restylane was launched in 1996, the development of proprietary Optimal Balance Technology™ offers new ranges of products that have been developed to suit patients’ individual needs. Diverse textures offer different levels of lift or volume, and some products are focused on improving the smoothness and appearance of the skin. Your healthcare professional now has a range of innovative Restylane solutions to tailor treatment to you – whether it’s to smooth wrinkles or lines, enhance facial balance, volumize your lips, or get a more radiant-looking glow. Or, all of these combined!

25 years of proof in real life

Louise, 65 years old, from Sweden, was one of the very first patients to be treated with Restylane in 1996. Louise has been continuously treated with Restylane over the past 25 years. She will continue to use the product to help her keep her natural look as she ages gracefully.

“Restylane has made me look like I feel. I like to feel fresh and like the age I am, not older. I feel amazing. That’s important to me.”



See one patient’s Restylane journey